BASELINE PREDICTORS OF SPUTUM CULTURE CONVERSION IN PULMONARY TUBERCULOSIS: IMPORTANCE OF CAVITIES, SMOKING, TIME TO DETECTION AND W-BEIJING GENOTYPE.

Baseline predictors of sputum culture conversion in pulmonary tuberculosis: importance of cavities, smoking, time to detection and W-Beijing genotype.

BackgroundTime to detection (TTD) on automated liquid mycobacterial cultures is an emerging biomarker of tuberculosis outcomes.The M.tuberculosis W-Beijing genotype is spreading globally, indicating a selective advantage.There is a paucity of data on the association between baseline TTD and W-Beijing genotype and tuberculosis outcomes.AimTo assess

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Optimizing cultivation of Cordyceps militaris for fast growth and cordycepin overproduction using rational design of synthetic media

Cordyceps militaris is an entomopathogenic fungus which is often used in Asia as a traditional medicine developed from age-old wisdom.Presently, cordycepin from C.militaris is a great interest in medicinal applications.However, cellular growth of C.militaris and the association with cordycepin production remain poorly understood.To explore the meta

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